Jornal de Nanomedicina e Nanotecnologia

Abstrato

Unique Chemical Bonding Behavior of Love Herbal Medicine and Its Ability as a Chemotherapy Drug

Arend Mapanawang and Hendry Izaac Elim

Love herbal (LH) medicine and its ability as chemotherapy drug is shown because of its ultra-large non-enzymatic antioxidant consisted mainly of ~6.54 ng/mL flavonoids with the calculated molecular resistant of, for example: neoflavonoid (RNf) about ~3 RC, in which RC is a resistant of carbon atom. Such promising medicine was fabricated using Halmahera susugolobe (Hornstedtiaalliacea), and then studied systematically about its multitasking behaviors. The obtained unique chemical bonding behavior especially related to a chemotherapy drug such as cisplatin (a commercial drug) is presented based on four main types of unique chemical bonds of N-H (Bending) at 1562 cm-1, C=C at 1697 cm-1, C≡C at 2070 cm-1, and C-H at 3013 cm-1. We found that only 3 bonds were closely in conjunction with LH medicine behavior as a chemotherapy drug. These three are N-H (Bending) at 1562 cm-1, C≡C at 2070 cm-1, and C-H at 3013 cm-1, where N-H (Bending) was fully responsible to handle the presence of toxic interacted to it. While the other two significant bonding of C≡C at 2070 cm-1, and C-H at 3013 cm-1 were in conjunction with the protective alkaline energy for the immune system in human body. Furthermore, LH medicine has healing activity as strong inhibition as Lamivudine (HIV drug invented in 1995) which is good in healing in HIV-AIDS patient and hepatitis virus. Such multiple findings open a breakthrough opportunity in healing cancer in a patient without side effects obtained using common chemotherapy drugs.