Jornal de Doenças Tropicais e Saúde Pública

Abstrato

Primary Adrenal Tumors in Adults Single Institute 10 Years ’ Experience

Ahmed Awad Sayed Salem, Mahmoud Hussein Alshoeiby, Badawy Mohammed Ahmed and Mona M Sayed

Introduction: The study aims to describe the clinico-pathological data of adult patients with different types of primary adrenal masses admitted to SECI and their outcome.

Patients and Methods: This is a retrospective study conducted at surgical oncology department, South Egypt cancer institute, Assiut University, from January 2006 till December of 2015. Ninety-six patients with proved primary suprarenal tumor were included in the study and their data were retrospectively collected. We tried to perform an epidemiological study and to evaluate the surgical outcome after adrenalectomy for either benign or malignant suprarenal tumors in term of intraoperative morbidity and short postoperative complications and long term follow up.

Results: A total of 96 adult patients diagnosed with primary suprarenal tumors (36 males and 60 females). Overall, 24 patients had benign lesions and 72 had malignant tumors (64 of cases had tumor size ≥ 6 cm). Hormonal evaluation was performed in all cases, which revealed hypersecretion in 10 cases, seventy-six patients underwent adrenalectomy, pathology was Adrenocortical carcinoma in 43 cases, Pheochromocytoma 22 cases, Adrenocortical hyperplasia 8 cases, paraganglioma 7 cases, Myelolipoma and adenoma 6 cases each, splenecule and suprarenal cyst 2 cases each. The mean of overall survival for malignant cases was 73.63 months.

Conclusion: The rarity of primary suprarenal tumours should not disprove their clinical significance because of their particular location and endocrine effects, and must be dealt with a multidisciplinary team to achieve cure and give the best survival values.