Genética hereditária: pesquisas atuais

Abstrato

Pleiotropy of Presenilins

Airong Li

Pleiotropy genes affect multiple and apparently unrelated phenotypes. Here we describe pleiotropy gene
presenilins, mutations in which have been detected in three genetically heterogeneous diseases: early-onset familial Alzheimer’s disease, familial or sporadic dilated cardiomyopathy, and familial hidradenitis suppurativa.