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Khat Chewing as a Risk Factor of Cigarette Smoking in Ethiopia Systemic Review and Meta-Analysis

Wosenyeleh Semeon Bagajjo, Kaleab Tesfaye Tegegne*, Demelash Zeleke, Andualem Zenebe, Abiyu Ayalew Assefa

Background: Tobacco use is a major public health issue and strongest lifestyle related with increase probability of Cardiovascular Disease (CVDs), the objective of this systemic review and meta-analysis was to determine whether khat chewing is risk factor of cigarette smoking In Ethiopia.

Methods: Eligible studies were identified by searching different databases like PubMed, Google Scholar and Web of science for published and unpublished articles; Data were extracted from the eligible studies using data abstraction form by two independent authors. Publication bias was assessed using the visual funnel plot and Egger’s test. Meta-analysis was performed by using random-effects models with the Der Simonian and Laird method.

Results: Eight studies were found to be eligible and included in the meta–analysis. Out of 3839 respondents 751(19.56%) were cigarette smokers. The proportion of cigarettes smoking among khat chewers and non khat chewers were 40.43% and 11.54% respectively. The final pooled effect size after trim and fill was found to be 1.93 (95%CI: 1.71, 2.14). This showed the presence of a significant association between khat chewing and cigarettes smoking.

Conclusions: Khat chewing were found to be significantly associated with cigarette smoking therefore, effective khat chewing prevention and intervention programs are required to reduce smoking among People in Ethiopia.

Isenção de responsabilidade: Este resumo foi traduzido usando ferramentas de inteligência artificial e ainda não foi revisado ou verificado