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Inhibition of Staphylococcus aureus by Corynebacterium Species: A Mini-Review

Sana Alibi

Staphylococcus aureus is a colonizer of human skin and nose. This asymptomatic carriage is an important risk factor of infection ranging from polymicrobial diabetic foot infection to monomicrobial bacteremia. Emergence of resistant bacteria, in particular, methicillin resistant S. aureus strains is a major health care problem worldwide. Looking for alternative ways to prevent S. aureus carriage and autoinfection is crucial. Some researchers focused on the study of the elimination of S. aureus by the implantation of nonpathogenic microorganisms. Corynebacterium spp., a common constituent of the human skin and mucosa, showed a potency to inhibit and decrease the virulence of S. aureus. In this mini-review, we will focus on the role of Corynebacterium species in the regulation of the virulence of S. aureus.