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Abstrato

Evaluation of Antibacterial Activity and Antioxidant Potential of Different Extracts from the Leaves of Juniperus Phoenicea

Maraia F. Elmhdwi, Idress Hamad Attitalla and Barkat Ali Khan

Medicinal

plants have recently received the attention of the antimicrobial activity of plants and their metabolites due to the challenge of growing incidents of drug-resistant

pathogens

. The aims of this study were to determine the antibacterial activities of the three extract (70% methanol, 70% ethanol and 70% acetone) from leaves of Juniperus phoenicea. Also effect as antioxidant of different extracts. For each solvent, content of total phenolics and flavonoids were quantified. Antioxidant activity of different extracts were screened using the ferric reducing power and 1, 1-diphenyl-2-picrylhydrazyl (DPPH•) radical scavenging. The results showed that 70% acetone is the best solvent for the extraction of total phenolics, flavonoids, scavenging activity and have exhibited the higher reducing power. The antibacterial activity of the three extractions from leaves of Juniperus phoenicea was evaluated against five

bacterial

strains. The results showed that all extracts of Juniperus phoenicea leaves at concentration of 20%, 30% and 40% were effective against both Gram-positive and Gram-negative bacteria. We suggest the three extraction solvents of Juniperus phoenicea leaves were rich in phenolic constituents. Our investigation allows us to support that Juniperus phoenicea has the antioxidant activity and is effective against all Gram-positive and Gram-negative bacteria.