Zara Qureshi*, Azharuddin M
Vaccines against SARS-CoV-2 infection have been hailed the biggest victory in the battle to control the pandemic. The safety of these vaccines has been the topic of much debate, particularly in the media. Overwhelmingly the data suggests they are safe. Around 6% of patients will develop mild to moderate symptoms for a few days. We present a case series of four patients who developed extremely rare complications in association with vaccination with recombinant Astra Zeneca SARS-CoV-2 vaccine namely Acute Inflammatory Demyelinating Polyneuropathy, Eosinophilic granulomatosis with polyangiitis and Multisystem Inflammatory Syndrome. As illustrated by these four cases, mass vaccination is not without risk and the receiving physician should be aware of these potential complications as well as other autoimmune mediated systemic illnesses, when assessing patients post vaccine. As mass vaccination programs continue worldwide, it is likely more cases demonstrating such complications will emerge.