Indexado em
- Banco de Dados de Periódicos Acadêmicos
- Abra o Portão J
- Genamics JournalSeek
- Chaves Acadêmicas
- JournalTOCs
- Infraestrutura Nacional de Conhecimento da China (CNKI)
- CiteFactor
- Scimago
- Diretório de Periódicos de Ulrich
- Biblioteca de periódicos eletrônicos
- RefSeek
- Universidade de Hamdard
- EBSCO AZ
- OCLC- WorldCat
- Catálogo online SWB
- Biblioteca Virtual de Biologia (vifabio)
- publons
- MIAR
- Comissão de Bolsas Universitárias
- Fundação de Genebra para Educação e Pesquisa Médica
- Euro Pub
- Google Scholar
Links Úteis
Compartilhe esta página
Folheto de jornal
Periódicos de Acesso Aberto
- Agro e Aquicultura
- Alimentos e Nutrição
- Bioinformática e Biologia de Sistemas
- Bioquímica
- Ciência de materiais
- Ciencias ambientais
- Ciências Clínicas
- Ciências Farmacêuticas
- Ciências gerais
- Ciências Médicas
- Cuidados de enfermagem e saúde
- Engenharia
- Genética e Biologia Molecular
- Gestão de negócios
- Imunologia e Microbiologia
- Neurociência e Psicologia
- Química
Abstrato
Analgesic Action by Neuroleptics in Diabetic State
Sadia Suri Kashif, Sadaf Naeem, Nausheen A Sarosh and Maqsood Ahmed Khan
Purpose: To assess the analgesic role of neuroleptics in hyperglycemic state.
Methods: Amytryptiline and carbamazepine were selected for study. This study was carried out at Pharmacology lab, Institute of Research Pharmaceutical sciences, University of Karachi, and comprised of male and female mice, half of which were made diabetic by giving Alloxan. The objective of this study is to monitor the effects of neuroactive agents on analgesic activity in hyperglycemic mice.
Results: It was observed that Amytryptiline exhibited highly significant analgesic effect in normal as compared to diabetic subjects. It was also observed that both amytryptiline and carbamazepine produce more rapid onset of action and longer duration of action in normal animals when compared with diabetic animals.
Conclusion: The present work on normal and diabetic animals show that both Carbamazepine and Amytryptiline in normal animals produce rapid onset and longer duration of action when compared with diabetic animals.