Farmacologia Cardiovascular: Acesso Aberto

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Amiodarone Use in Pre-Heart Transplant Patients and its Effect on Graft Function and Mortality

Roy Lee, Kent Nilsson and Amin Yehya

Amiodarone is a commonly used agent to treat life-threatening cardiac arrhythmias in patients with heart failure. While survival after heart transplantation has improved greatly over the decades, the use of amiodarone prior to transplant is controversial. Some reports describe graft dysfunction and increased risk of mortality post-transplant in patients that are exposed to amiodarone pre-operatively, while others do not. Here, we review and summarize the available literature on this topic.