Jornal de Nanomedicina e Nanotecnologia

Abstrato

: Ascaridia galli (chicken nematode) as a Source for Nanoparticle and Nanofiber

Sunila Kumari

Green synthesis of nano particles and nanofiber gained relevance in recent times. Ideally nanoparticles and nanofiber are made from metallic sources. However, in recent times, there are reports of drastic side effects about the use of metallic nanoparticles in biology and medicine. In this context, it has become more relevant to explore and identify, more natural and biofriendly and effective alternative to metallic ones. There are instances, where, nanoparticles and nanofibers, and many other nano components, have been synthesized from more natural sources, such as bacteria, different species of algae and also from fungi. However, not many have attempted to synthesize nanoparticles, from unusual sources such as nematodes, the intestinal parasites of animals and humans. For the first time, in the present study it was attempted to synthesize nanoparticles and nanofiber from the intestinal nematode of chicken, Ascaridia galli. The parasites, were extracted and isolated from the chicken intestines, they were later processed for the synthesis of nanoparticle and nanofiber. It is quite evident that nanoparticles, synthesized from a natural source are more appealing as they are both ecofriendly and inexpensive. Parasite, measuring approximately 4 to 5cms in length were carefully removed from chicken intestines and later processed for the synthesis of nanoparticle and nanofiber. Nanoparticles were synthesized using the method of acid hydrolysis and nanofiber was prepared using electro spinning technique. The nanofibre which was synthesized was hydrophilic in nature. Scanning electron microscope (SEM) images of nanoparticle revealed a diameter of 48.46nm- 20μm and the nanofiber diameter was found to be between 88nm-2 μm, thus matching to the average standard size of nano particle and nanofiber. As the intestinal parasites, are capable of evading host immunity and can easily amalgamate with the host tissues, without triggering any antagonism, therefore can be used frequently in biology and medicine. As these nanoparticles and nanofiber, are synthesized using a parasite,(a living source) it can easily be degraded after the use, and may be considered as a suitable alternative to metallic nanomaterials.

Nanoparticle; Nanofiber; Ascaridia galli; Acid hydrolysis, Electro spinning; SEM; Chicken nematode